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4. Pupil Dilation
If you or someone else notices that your pupils are dilated when they should not be, it is a good indicator of serotonin syndrome. Dilated pupils happens when the black of the eye are bigger than normal when light conditions are ample. Under usual circumstances, pupil dilation only occurs when little light is available as this helps with vision in the dark.
This symptom is easily tested. You can test pupil dilation by shining a gentle light source in the eye and observe in the mirror if it shrinks or stays the same. The neurotransmitters which control the muscles involved with pupil dilation are affected by the high serotonin levels.
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